The sneaky, underhanded ways of Bovine Viral Diarrhea Virus
The sneaky, underhanded ways of Bovine Viral Diarrhea Virus

The Sneaky, Underhanded Ways of Bovine Viral Diarrhea Virus

Easy to Catch, Hard to Detect

  • BVDV is a highly contagious virus that can infect both beef cattle and dairy cattle
  • Most infections are subclinical, meaning cattle show few or no signs
  • The virus mutates and changes over time
  • The most common BVDV subtypes include Type 1b, which is the most prevalent strain, Type 1a and Type 21
  • BVDV can contribute to reproductive disease (abortions, persistently infected calves and birth defects), respiratory disease and, less commonly, diarrhea

Economic Impact

  • Poor reproduction
    • Decreased or delayed conception
    • Early embryonic death
    • Abortions and stillborns
    • Birth defects, weak calves
    • Longer calving intervals
  • Persistently infected (PI) calves
  • Increased incidence of other bovine health problems
    • Mastitis, decreased milk production
    • Bovine respiratory disease/Pneumonia
    • Calf scours
  • Increased mortality

How BVDV Is Spread

Image showing how vertical transmission of BVDV can move in cattle

1. From a Persistently Infected (PI) Dam to the Fetus:

If they’re able to viably gestate, PI dams will always produce PI calves. Many will die before 1 year of age; others typically show no clinical signs.

How BVDV spreads portrayed in graphic form

2. From a Transiently Infected Dam to the Fetus:

Calves that become infected in the uterus can be born PI, spreading the virus for a lifetime.

How horizontal transmission works in Cattle BVDV

3. From PI or Acutely Infected Cattle to Healthy Cattle:

Infected animals can shed the virus in saliva, nasal and eye discharge, urine, feces, milk and semen. Infection then occurs from nose-to-nose contact or when the virus is ingested or inhaled.

Two Types of Infection

Persistent infection - 5% of infections
  1. 1. Acquired from dam while in uterus
  2. 2. Lasts a lifetime
  3. 3. Major source of viral shedding
Transient infection - 95% of infections
  1. 1. Acquired from other animals after birth
  2. 2. Lasts a few weeks
  3. 3. Minor source of viral shedding

Most Infected Cattle Escape Detection

  • 70–90% of BVDV infections are subclinical (no obvious signs) and go unnoticed
  • Infection suppresses the immune system, making cattle more susceptible to other infectious diseases:
    • In calves, may result in decreased weaning weight, scours, pneumonia and death
    • In older animals, may lead to respiratory disease and bleeding disorders
  • Most common indication is poor reproductive performance: decreased conception rates, abortions, stillbirths, weak calves

Signs of Transient Infection

Signs can vary from mild to severe and may include:

  • Depression
  • Loss of appetite
  • Decreased milk production
  • Increased respiratory rate
  • Nasal and/or eye discharge
  • Diarrhea
  • Oral ulcers
  • Fever
  • Death

PI Calves: A Risk for the Rest of Your Herd

Persistently infected calves often appear normal, but continually spread the virus on your operation.

References

1 Fulton RW, Cook BJ, Payton ME, et al. Immune response to bovine viral diarrhea virus (BVDV) vaccines detecting antibodies to BVDV subtypes 1a, 1b, 2a and 2c. Vaccine 2020:38(24);4032–4037.

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