ToDAY® (cephapirin sodium)

Two-tube mastitis treatment

 

Details

  • ToDAY is an antibiotic mastitis treatment providing bactericidal activity against Gram-positive and Gram-negative bacteria in lactating dairy cows.

  • Each 10-mL disposable, ready-to-use syringe contains the active ingredient cephapirin sodium.

  • Provides control against mastitis-causing pathogens including penicillin-resistant Staphylococcus aureus  and  Streptococcus agalactiae.

  • Easy two-tube treatment given 12 hours apart.

  • When the Opti-Sert® cap is removed, a collar allows only a 3-mm tip to be inserted into the teat canal, helping to reduce the incidence of new infections.5


Presentations

  • Pail containing 144 x 10 mL syringes and 144 convenient single-use alcohol pads.

  • Cartons containing 12 x 10 mL syringes with 12 convenient single-use alcohol pads.

Features & Benefits

Proven Efficacy

Two treatments of ToDAY showed no difference in overall bacteriologic clinical cure rates when compared to five tubes of Spectramast® LC (ceftiofur hydrochloride).2

 

Think Positive

Intramammary mastitis treatment of Gram-positive infections is widely reported as beneficial,⁴ so those infections should be the focus of treatment.¹

 

Short Duration

Administering two syringes of ToDAY results in a short-duration milk discard of 108 hours' (4.5 days) time out-of-tank so you can return the cow to producing sellable inventory. 


Learn more about treating infection vs. inflammation (PDF).

Dosage & Administration

Infuse a 10-mL syringe (200 mg of cephapirin activity per syringe) once the quarter has been completely milked out. Repeat once only in 12 hours. For lactating cows only. Read and follow label directions.
 

Image
Opti-Sert Applicator Tip

Additional Administration Information:

Resources
Safety

Residue Warnings:

Milk that has been taken from animals during treatment and for 96 hours after the last treatment must not be used for food. Treated animals must not be slaughtered for food until four days after the last treatment. Administration of more than the prescribed dose may lead to residue of antibiotic in milk longer than 96 hours.

ToDAY should be administered with caution to subjects that have demonstrated some form of allergy, particularly to penicillin. Such reactions are rare; however, should they occur, consult your veterinarian.

Better for Everyone
Better for Everyone

Save Time, Milk and Money

Choosing a short-duration treatment protocol allows you to treat mastitis with fewer antibiotics than a five-day protocol, without sacrificing efficacy.

Dairy cow
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Technical Bulletins

ToDAY Compared To Spectramast® LC

A Non-inferiority Trial Comparing a First-Generation Cephalosporin with a Third-Generation Cephalosporin in the Treatment of Non-Severe Clinical Mastitis in Dairy Cows

> Read the Technical Bulletin

 

Minimum Inhibitory Concentrations Study

Minimum Inhibitory Concentrations (MIC) for Cephalosporin Compounds on Their Active Metabolites for Selected Mastitis Pathogens

> Read the Technical Bulletin

References

1. Keefe G, MacDonald K, Cameron M. On-farm culture use experience and impact on antimicrobial use. University of Prince Edward Island, Charlottetown, PE, Canada.

2. Schukken YH, Zurakowski MJ, Rauch BJ, et al. Non-inferiority trial comparing a first-generation cephalosporin with a third-generation cephalosporin in the treatment of nonsevere clinical mastitis in dairy cows. J Dairy Sci 2013;96(10):6763–6774.

3. Nydam D, Virkler P, Capel M, et al. Pathogen-based treatment decisions for clinical mastitis, in Proceedings. NMC Regional Meeting 2015;1-4.

4. Hess JL, Neuder LM, Sears PM. Rethinking clinical mastitis therapy, in Proceedings. 42nd Annu Meet of the NCM 2003:372–373.

5. Boddie RL, Nickerson SC and Sutherland SF. New design of mastitis tubes reduces infection. Hoard’s Dairyman, August 1989, 134(13)579.

Trademarks

ToDAY® is a registered trademark of Boehringer Ingelheim Animal Health USA Inc. All other trademarks are property of their respective owners. ©2021 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All Rights Reserved.
US-BOV-0386-2021

US-BOV-0386-2021