FREE TO MOVE is more than just our comprehensive joint health portfolio. It’s how we want every horse to feel.
Learn more about degenerative joint disease, and discover our full joint health product portfolio at the link below.
Equioxx®
(firocoxib)
The pioneer COXIB class NSAID with a decreased potential for risks commonly associated with nonselective NSAIDs.1
Details
EQUIOXX for horses controls pain and inflammation associated with osteoarthritis for up to 24 hours with each dose.
A horse’s joints often need medical support in order to relieve the pain and inflammation associated with equine osteoarthritis. Equine osteoarthritis can happen in any age and any discipline due to everyday wear and tear. It is permanent and can lead to early retirement and quality of life issues in horses.
EQUIOXX is a COXIB class non-steroidal anti-inflammatory for horses that helps to manage the roller-coaster effect of pain and pain relief that can occur with other products which might require multiple daily dosing.
EQUIOXX is available in two formulations: paste and tablet. EQUIOXX tablets are small and palatable enough to be hand-fed with or without feed. EQUIOXX paste provides more accurate dosing by weight for smaller horses or competition horses subject to testing.
As with any prescription medication, prior to use, a veterinarian should perform a physical examination and review the horse’s medical history. A veterinarian should advise horse owners to observe for signs of potential drug toxicity. Use with other NSAIDs, corticosteroids or nephrotoxic medication should be avoided.
Features & Benefits
Features
-
Each dose controls pain and inflammation associated with osteoarthritis in horses for up to 24 hrs
-
EQUIOXX has been tested on more horses in safety studies than any other NSAID
-
The first and only cyclooxygenase-inhibiting (COXIB) class nonsteroidal anti-inflammatory drug (NSAID) approved for horses
-
Available in two formulations: paste and tablet
Benefits
-
Proven efficacy and a safety profile supported by science
-
COXIB class NSAIDs have a decreased potential for risks commonly associated with nonselective NSAIDS such as phenylbutazone
-
Two formulations allow for drug administration options that help to meet the needs of each client and patient
-
EQUIOXX paste allows best dosing accuracy
Dosage & Administration
EQUIOXX can only be used by or on the order of a veterinarian. Once you have obtained a prescription, EQUIOXX is made for easy administration by an owner. EQUIOXX Oral Paste or Tablets can be used at a dosage of 0.045 mg/lb (0.1 mg/kg) body weight once daily for up to 14 days.
The recommended dosage of EQUIOXX Oral Paste is 0.045 mg/lb (0.1mg/kg) body weight, once daily for up to 14 days. For EQUIOXX Paste, each marking on the syringe will treat 250 pounds of body weight.
The recommended dosage of EQUIOXX Tablets is one 57 mg tablet administered orally to horses weighing 800-1300 lbs, (0.04-0.07mg/lb or 0.09-0.15 mg/kg), once daily for up to 14 days.
A veterinarian should advise horse owners to observe for signs of potential drug toxicity. As a class, nonsteroidal anti-inflammatory drugs may be associated with gastrointestinal, hepatic and renal toxicity. Use with other NSAIDs, corticosteroids or nephrotoxic medication should be avoided.
For more information please read EQUIOXX Tablets Product Insert and EQUIOXX Paste Product Insert.
Resources
Safety Information
As with any prescription medication, prior to use, a veterinarian should perform a physical examination and review the horse’s medical history. A veterinarian should advise horse owners to observe for signs of potential drug toxicity. As a class, nonsteroidal anti-inflammatory drugs for horses may be associated with gastrointestinal, hepatic and renal toxicity. Use with other NSAIDs, corticosteroids or nephrotoxic medication should be avoided. EQUIOXX has not been tested in horses less than 1 year of age or in breeding horses, or pregnant or lactating mares.
How Equioxx® (firocoxib) works
EQUIOXX selectively blocks the COX-2 isoenzyme which is the form that generates the prostaglandins mostly responsible for pain and inflammation. Yet it spares cyclooxygenase 1-isoenzyme (COX-1), which helps maintain normal body functions such as coagulation, gastric mucosal protection and blood flow to the kidneys.2,3,4
References
1 Kvaternick V, Pollmeier M, Fischer J, Hanson PD. Pharmacokinetics and metabolism of orally administered firocoxib, a novel second-generation coxib in horses. J Vet Pharmacol Ther 2007;30(3):208–217
2 Data on file at Boehringer Ingelheim. Clinical Experience Report PHN 471, PR&D 0030701.
3 Data on file at Boehringer Ingelheim, Clinical Experience Report PHN 471, Target Animal Safety Evaluation, Firocoxib (ML-1, 785, 713) Oral Paste for Horses
4 Warner TD, Mitchell JA. Cyclooxygenase-3 (COX-3): Filling in the gaps toward a COX continuum? in Proceedings Natl Acad Sci USA 2002;99(21):13371–13373.
Trademarks
EQUIOXX® is a registered trademark of Boehringer Ingelheim Animal Health USA Inc. ©2023 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All Rights Reserved. US-EQU-0116-2021-V2