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PREVICOX® (firocoxib) Chewable Tablets

INDICATIONS

PREVICOX® (firocoxib) Chewable Tablets are indicated for the control of pain and inflammation associated with osteoarthritis (OA) in dogs and for the control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery in dogs.

CLINICAL BENEFITS

Proven Efficacy Veterinarians and Pet Owners Notice

  • In a study, 96% of pet owners said they saw improvement after 30 days, and veterinarians saw improvement in 93% of their canine osteoarthritis (OA) patients1

 

Rapid Absorption

  • Detected in plasma within 30 minutes with peak plasma levels reached as early as 90 minutes*2

*Clinical relevance has not been demonstrated.

 

Easy Dosing

  • Once-daily dosing regardless of indication, 2.27 mg/lb (5.0 mg/kg)

  • Only 2 tablet sizes

  • Scored tablet for convenient, effective dosing

    • Designed to maximize compliance with simple, effective dosing

    • BBQ-flavored chewable tablets that are highly accepted by dogs3

    • Can be given with or without food: while some NSAIDs are recommended to be taken with food, PREVICOX® (firocoxib) Chewable Tablets can be taken with or without a meal

  • No loading dose required

 

Safe When Used as Recommended

  • Approved for long term use4

  • Comparable adverse events (AEs) in 30-day OA field studies vs active NSAID control5

 

Approved Safe for Surgical Use

  • In a soft-tissue surgery study, 94% of dogs treated with PREVICOX Chewable Tablets needed no rescue medication* versus 76% of dogs on placebo dose control6

  • In an orthopedic surgery study, 90% of dogs treated with PREVICOX Chewable Tablets needed no rescue medication* versus 62% of dogs on placebo dose control7

  • Consistent dosing across all indications

    • When used peri- and postoperatively, there is no need for a washout period from the perioperative NSAID and the NSAID you send home with your patient

    • Allows the pet to have continuous pain and inflammation control throughout and after surgery, and gives pet owners peace of mind knowing their dog will not go without pain medication following surgery

*A rescue medication is used to immediately relieve clinical signs.

DOSAGE & ADMINISTRATION

Always provide Client Information Sheet with prescription. Carefully consider the potential benefits and risks of PREVICOX® (firocoxib) Chewable Tablets and other treatment options before deciding to use PREVICOX. Use the lowest effective dose for the shortest duration consistent with individual response.  

 

The recommended dosage of PREVICOX Chewable Tablets for oral administration is 2.27 mg/lb (5.0 mg/kg) once daily, regardless of the indication, and can be given with or without food. PREVICOX Chewable Tablets are available in 2 BBQ-flavored chewable tablet sizes that are highly accepted by dogs.3

 

Use for Osteoarthritis

Dogs can be treated with PREVICOX Chewable Tablets once daily for long-term use or as needed to control pain and inflammation associated with osteoarthritis (OA).

 

Use for Surgery

Dogs can be treated with PREVICOX Chewable Tablets approximately 2 hours prior to soft-tissue or orthopedic surgery, and the treatment can be continued once a day for up to 3 days to control postoperative pain and inflammation.

 

Dosage Chart*

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Chart displaying the correct dosages for pets of various weight ranges

*Daily dose is 2.27 mg/lb (5.0 mg/kg). The above is a practical dosing guide. 

SAFETY

Contraindications:  Dogs with known hypersensitivity to firocoxib should not receive PREVICOX® (firocoxib) Chewable Tablets.

 

Warnings: Not for use in humans. Keep this and all medications out of the reach of children. Consult a physician in case of accidental ingestion by humans.

 

For oral use in dogs only. Use of this product at doses above the recommended 2.27 mg/lb (5.0 mg/kg) in puppies less than 7 months of age has been associated with serious adverse reactions, including death.

 

Due to tablet sizes and scoring, dogs weighing less than 12.5 lb (5.7 kg) cannot be accurately dosed.

 

Precautions: The safe use of PREVICOX Chewable Tablets in pregnant, lactating, or breeding dogs has not been evaluated.

 

As a class, cyclooxygenase inhibitory NSAIDs like PREVICOX Chewable Tablets may be associated with gastrointestinal, kidney, or liver side effects.  

 

Concurrent use with another NSAID, corticosteroid, or nephrotoxic medication should be avoided or monitored closely. Dogs should be evaluated for pre-existing conditions and currently prescribed medications prior to treatment with PREVICOX Chewable Tablets, then monitored regularly while on therapy.

 

For more information, please see full prescribing information.

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Specifically Designed for Dogs

Designed to provide fast and effective pain relief delivered in a barbeque-flavored, once-daily, chewable tablet that is safe, effective, and well tolerated by dogs.3 Compared to some non-specific canine NSAIDs, PREVICOX Chewable Tablets don’t require a loading dose, and use the same dosing across all indications.

Surgical and 
OA Pain Relief

Make PREVICOX Chewable Tablets your go-to NSAID for proven relief...

Make PREVICOX Chewable Tablets your go-to NSAID for proven relief from the pain and inflammation caused by canine OA, soft-tissue surgery, and orthopedic surgery.6,7

Safety and Efficacy

PREVICOX Chewable Tablets are highly efficacious, providing fast-acting,..

PREVICOX Chewable Tablets are highly efficacious, providing fast-acting, sustained, and noticeable pain relief with a well-established safety profile.

Dosing

While some NSAIDs are recommended to be taken with food,..

While some NSAIDs are recommended to be taken with food, PREVICOX Chewable Tablets can be taken with or without a meal. Plus, the dosage of PREVICOX Chewable Tablets is the same for acute post-op pain and chronic OA pain.

 

Get Your 2% Savings

Take advantage of a 2% discount when purchasing PREVICOX Chewable Tablets through BI-CONNECT. Note: additional savings over 2% available throughout the year.

IMPORTANT SAFETY INFORMATION

PREVICOX® (firocoxib) Chewable Tablets are for use in dogs only. As a class, cyclooxygenase inhibitory NSAIDs like PREVICOX may be associated with gastrointestinal, kidney, or liver side effects. Dogs should be evaluated for pre-existing conditions and currently prescribed medications prior to treatment with PREVICOX, then monitored regularly while on therapy. Concurrent use with another NSAID, corticosteroid, or nephrotoxic medication should be avoided or monitored closely.  For more information, please see full prescribing information.

Compare PREVICOX Chewable Tablets With GALLIPRANT® (grapiprant tablets)

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Indicated for the control of pain and inflammation associated with canine osteoarthritis.1
 
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Additional surgical indications including control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery in dogs.6,7
 
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For dogs 7 months of age or older.
 
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Can be given with or without food.
 
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Has the downstream effect of decreasing activity on the major EP receptors associated with pain and inflammation. All 4 EP receptors are thought to be involved in OA pain and inflammation.

 

 

VS

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Indicated for the control of pain and inflammation associated with canine osteoarthritis.
 
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Approved for use in soft-tissue surgery.
 
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Approved for use in orthopedic surgery.
 
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Can be given with or without food.

Note: Performance diminishes if given with food.

 
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Works only on inhibiting activity at the prostaglandin (PGE2) EP4 receptor, leaving potential gaps in controlling pain and inflammation.

PREVICOX is a great drug because it is approved for soft-tissue pain and orthopedic pain, and it also is approved for osteoarthritis, so a dog that has OA will not have to be switched over.

—Dr. Jennifer Bornkamp, MS, DVM, CVTP, CVA Pittsburgh Veterinary Specialty Center and Emergency Center

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MOBILITY MASTERS™

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MOBILITY MASTERS™

Boehringer Ingelheim has developed an OA certification program to help veterinary technicians expand their knowledge, advocacy, and skill sets to master OA management. The certification program provides a variety of resources, education, and instructional material including:

  • Webinars

  • On-demand courses

  • Elective materials

  • In-clinic posters

  • Handouts, such as OA checklists

  • Social media posts

  • Workbooks

 

Coming Soon

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Pain Management Portfolio

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With a comprehensive portfolio of trusted and proven pain and inflammation management, Boehringer Ingelheim continues to build upon its long-standing history of leadership in the NSAID market.

References
  1. Pollmeier M, Toulemonde C, Fleishman C, Hanson PD. Clinical evaluation of firocoxib and carprofen for the treatment of dogs with osteoarthritis. Vet Rec. 2006;159(17):547–551.
  2. Data on file at Boehringer Ingelheim.
  3. PREVICOX® (firocoxib) Chewable Tablets [Freedom of Information Summary; NADA 141-230]. Duluth, GA:Boehringer Ingelheim Animal Health USA Inc.; 2004.
  4. Autefage A, Palissier FM, Asimus E, Pepin-Richard C. Long-term efficacy and safety of firocoxib in the treatment of dogs with osteoarthritis. Vet Rec. 2011;168(23):617-617. doi:https://doi.org/10.1136/vr.d1456
  5. PREVICOX® (firocoxib) Chewable Tablets [prescribing information]. St. Louis, MO: Boehringer Ingelheim Animal Health USA Inc.; 2019.
  6. PREVICOX® (firocoxib) Chewable Tablets [Freedom of Information Summary; NADA 141-230 Supplemental Approval]. Duluth, GA: Boehringer Ingelheim Animal Health USA Inc.; 2007.
  7. PREVICOX® (firocoxib) Chewable Tablets [Freedom of Information Summary; NADA 141-230 Supplemental Approval]. Duluth, GA: Boehringer Ingelheim Animal Health USA Inc.; 2008.
Trademarks

PREVICOX® is a registered trademark and BI-CONNECT™ is a trademark of Boehringer Ingelheim Animal Health USA Inc. METACAM® is a registered trademark and MOBILITY MASTERS™ is a trademark of Boehringer Ingelheim Vetmedica GmbH, used under license. All other trademarks are the property of their respective owner. ©2023 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved.

US-PET-0737-2022-A

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