Available as chewable tablets or an oral solution for managing congestive heart failure (CHF) due to myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM) in dogs.
Same Effective Treatment,
Two Convenient Formulations
VETMEDIN® Solution (pimobendan oral solution)
- The same VETMEDIN treatment you’ve prescribed for your CHF patients for years is also available in a liquid oral solution.
- Newly available VETMEDIN Solution makes administration easy for dogs who prefer liquid medication and delivers just the right dose they need.
VETMEDIN® (pimobendan) Chewable Tablets
- Studies have demonstrated that VETMEDIN Chewable Tablets can increase survival and improve quality of life for stage C & D CHF Patients.1,2
- Beef-flavored chewable tablets are half-scored to meet the dosing needs of patients who prefer chews.
Approved by
the FDA
VETMEDIN is the only brand approved by the FDA that includes both tablet and liquid formulations to manage dogs with CHF due to MMVD and DCM.
Unique Dual
Mode of Action
Unique dual mode of action demonstrated increased survival time and improved quality of life compared to ACE inhibitors as shown in previous studies.1-3
ACVIM-Consensus
Recommended
American College of Veterinary Internal Medicine (ACVIM) consensus guidelines recommended as a first-line therapy for dogs in heart failure due to MMVD or DCM.*3
VETMEDIN (pimobendan) should not be administered in cases of hypertrophic cardiomyopathy, aortic stenosis, or any other clinical condition where an augmentation of cardiac output is inappropriate for functional or anatomical reasons
INDICATIONS
VETMEDIN Chewable Tablets and VETMEDIN Solution are indicated for the management of the signs of mild, moderate, or severe congestive heart failure (CHF) in dogs due to clinical myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM). Both formulations of VETMEDIN are indicated for use with concurrent therapy for congestive heart failure (eg., furosemide) as appropriate on a case-by-case basis.
CLINICAL BENEFITS
VETMEDIN® Brand Products feature a mode of action that acts as both a positive inotrope and potent,
balanced vasodilator, simultaneously dilating veins and arteries. In these forms, the product enters the GI
tract and is rapidly absorbed.
- Proprietary formulation ensures optimal bioavailability that in turn ensures optimal therapeutic effect.
- In clinical studies, the dual mode of action demonstrated increased survival time and improved quality of life compared to ACE inhibitors.1,2
- Published evidence shows improved clinical parameters and reduced heart size when compared to dogs on ACE inhibitors.3
- Recommended by American College of Veterinary Internal Medicine (ACVIM) Specialty of Cardiology consensus panel guidelines as part of first-line therapy in dogs diagnosed with heart failure to ensure optimal patient outcomes.4
- The beef-flavored chewable tablet ensures high levels of acceptability that in turn promotes compliance.5,6
- The oral solution formulation makes it easy to give dogs who prefer liquid medication.
- Meets FDA standards of product efficacy, stability, and strength.
DOSAGE & ADMINISTRATION
VETMEDIN® Chewable Tablets
VETMEDIN Chewable Tablets should be administered orally at a total daily dose of 0.23mg/lb (0.5 mg/kg) body weight.
- The total daily dose should be divided into 2 portions that are not necessarily equal, and the portions should be administered approximately 12 hours apart (ie, morning and evening).
- Any suitable combination of whole or half tablets may be used.
- The tablets are scored, and the calculated dosage should be provided to the nearest half-tablet increment.
See the VETMEDIN Chewable Tablets Dosing Chart
VETMEDIN® Solution
VETMEDIN Solution should be administered orally at a total daily dose of 0.23 mg/lb (0.5 mg/kg) body weight.
- The total daily dose should be divided into 2 equal portions administered approximately 12 hours apart (i.e., morning and evening).
- VETMEDIN Solution should be administered directly into the mouth. Do not mix into food.
- VETMEDIN Solution should be administered using the orange dosing syringe provided in the package. The syringe is calibrated to deliver the appropriate morning or evening dose when drawn to the dog’s nearest weight in pounds.
Do not shake the bottle before or during use to avoid foaming.
See the VETMEDIN Solution Dosing Chart
SAFETY
Contraindications: VETMEDIN (pimobendan) should not be given in cases of hypertrophic cardiomyopathy, aortic stenosis, or any other clinical condition where an augmentation of cardiac output is inappropriate for functional or anatomical reasons.
Warnings: Only for use in dogs with clinical evidence of heart failure. At 3 and 5 times the recommended dosage, administered over a 6-month period of time, pimobendan caused an exaggerated hemodynamic response in the normal dog heart, which was associated with cardiac pathology. Keep VETMEDIN in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.
Human Warnings: Not for use in humans. Keep this and all medications out of reach of children. Consult a physician in case of accidental ingestion by humans.
Precautions: The safety of VETMEDIN has not been established in dogs with asymptomatic heart disease or in heart failure caused by etiologies other than myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM). The safe use of VETMEDIN has not been evaluated in dogs younger than 6 months of age, dogs with congenital heart defects, dogs with diabetes mellitus or other serious metabolic diseases, dogs used for breeding, or pregnant or lactating bitches.
Adverse Reactions: The most common side effects reported in field studies were poor appetite, lethargy, diarrhea, dyspnea, azotemia, weakness, and ataxia.
For more information, please see full prescribing information for Solution, or full prescribing information for Chewable Tablets.
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Additional Resources from CEG
The Cardiac Education Group (CEG) is a not-for-profit of board-certified veterinary cardiologists, with resources on the diagnosis, treatment, and management of heart disease in dogs and cats.
US-PET-0653-2020-V3