Species

PUREVAX® Recombinant FeLV

DETAILS

PUREVAX® Recombinant FeLV contains a nonadjuvanted lyophilized suspension of a recombinant vectored feline leukemia vaccine plus sterile water diluent. A canarypox vector has been modified using recombinant technology to produce expression of desired antigens capable of stimulating a protective immune response to feline leukemia. Safety and immunogenicity of this product have been demonstrated by vaccination and challenge tests in susceptible cats.

INDICATIONS

This product has been shown to be effective for the vaccination of healthy cats, 8 weeks of age or older, against feline leukemia virus. The duration of immunity has not been determined. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.

DOSAGE & ADMINISTRATION

Aseptically rehydrate the lyophilized vaccine with 0.5 mL of the accompanying sterile water diluent and agitate. Administer 1 dose subcutaneously. For primary vaccination, cats should receive 2 doses, 3 weeks apart. Diagnostic testing for FeLV prior to vaccination is recommended.

PRECAUTIONS

Precautions: Use entire contents immediately following rehydration. Contains gentamicin as a preservative. This product has not been tested in pregnant cats. In rare instances, administration of vaccines may cause transient pain associated with injection, lethargy, fever, and inflammatory or hypersensitivity types of reactions. Treatment may include antihistamines, anti-inflammatories, and/or epinephrine. In case of human exposure, contact a physician. Inactivate unused contents before disposal.

 

Store at 2-8ºC (35-46ºF). Do not use chemicals to sterilize syringes and needles. Do not mix with other products, except as specified on the label.

 

For use in animals only. Restricted to use by or under the direction of a veterinarian.

Unique Technology Makes the Difference

  • PUREVAX Recombinant FeLV is the first and only recombinant canarypox-vectored nonadjuvanted feline leukemia virus (FeLV) vaccine.

  • PUREVAX FeLV provides efficacy equivalent to killed, adjuvanted FeLV vaccines.1 
Two vets smile at a cat

Benefits of PUREVAX® Feline Vaccines

Safe, effective, and pure without adjuvants. Here are a few of the many benefits of PUREVAX® feline vaccines:

  • All PUREVAX feline vaccines utilize either modified live (ML) or recombinant canarypox-vectored technology, which stimulate both humoral and cell-mediated immune responses.2,3

  • Recombinant canarypox-vectored vaccines contain only a portion of the genetic material of a pathogen, not the complete pathogenic organism. Therefore there is no potential for reversion to virulence.

  • With half-mL doses, the PUREVAX brand continues to innovate for the evolving needs of veterinarians and their patients.
See Detailer

Benefits of PUREVAX® Feline Vaccines

Safe, effective, and pure without adjuvants. Here are a few of the many benefits of PUREVAX® feline vaccines:

  • All PUREVAX feline vaccines utilize either modified live (ML) or recombinant canarypox-vectored technology, which stimulate both humoral and cell-mediated immune responses.2,3

  • Recombinant canarypox-vectored vaccines contain only a portion of the genetic material of a pathogen, not the complete pathogenic organism. Therefore there is no potential for reversion to virulence.

  • With half-mL doses, the PUREVAX brand continues to innovate for the evolving needs of veterinarians and their patients.
See Detailer
Two vets smile at a cat

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References
  1. Grosenbaugh DA, Frances-Duvert V, Abedi S, Feilmeier B, Ru H, Poulet H. Efficacy of a nonadjuvanted recombinant FeLV vaccine and two inactivated FeLV vaccines when subject to consistent virulent FeLV challenge conditions. Biologicals. 2017;49:76-80.

  2. Greene CE, Schultz RD. Immunoprophylaxis. In: Greene CE, ed. Infectious Diseases of the Dog and Cat. 4th ed. St Louis, MO: Elsevier Saunders; 2012:1166-1169.

  3. Taylor J, Meignier B, Tartglia J, et al. Biological and immunogenic properties of canarypox-rabies recombinant, ALVAC-RG (vCP65) in non-avian species. Vaccine. 1995; 13;6;539-549.

  4. Data on file at Boehringer Ingelheim.

  5. McNeil MM, DeStefano F. Vaccine-associated hypersensitivity. J Allergy Clin Immunol. 2018;141(2):463-472.

  6. Day MJ, Schoon H-A, Magnol J-P, et al. A kinetic study of histopathological changes in the subcutis of cats injected with non-adjuvanted and adjuvanted multi-component vaccines. Vaccine. 2007; 25:4073-4084.
Trademarks

RECOMBITEK® and IMRAB® are registered trademarks and BI-CONNECT™ is a trademark of Boehringer Ingelheim Animal Health USA Inc. PUREVAX® is a registered trademark of Boehringer Ingelheim Animal Health France, used under license. ©2023 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved.

US-PET-0234-2021-C-V2