PROZINC® (protamine zinc recombinant human insulin) treatment for diabetes mellitus is the only FDA-approved veterinary insulin made with recombinant technology. It’s the only product scientifically formulated with protamine zinc to support optimal glycemic control and extended duration of action. Read on to learn more about PROZINC insulin.
Trusted Canine and Feline Diabetes Care
Backed by both the largest US clinical canine insulin study to date, including 276 canine patients, and the largest prospective feline insulin study to date, including 151 feline patients, you can be confident in the power of PROZINC insulin to maintain glycemic control and reduce clinical signs.1,2
- 88% showed improvement in excessive thirst1
- 90% showed improvement in excessive urination1
- 72% achieved diabetic control1
- 76% showed improvement in excessive thirst2,3
- 74% showed improvement in excessive urination2,3
- Approximately half showed improvement in as soon as 7 days 2,3
Diabetes Communication Made Simple
Meet Barry the body cell! He's here to lay down the PROZINC insulin difference, and make it easier to communicate with your staff about the complexities of diabetes.
Mode of Action
Watch the extended-release formulation of PROZINC insulin at work.
Listen to Reliable Diabetes Control in Action
Insulin Therapies in Dogs and Cats
Grant Beckett, BVSc, MRCVS, MMD, Boehringer Ingelheim Animal Health & Cassi Flemming, MS, DVM, VetFolio (NAVC)
Diabetes is the most common endocrine disease in cats and dogs. The FDA approved a single injection insulin protocol for dogs, which can provide reliable control of clinical signs of diabetes for 18>24 hours in most canine patients. Once-a-day administration of PROZINC insulin is more convenient for dog owners, which in many cases results in a better quality of life for their diabetic dogs.
Ready to Try PROZINC Insulin?
Make FDA-approved PROZINC insulin your first-line treatment for canine and feline diabetic patients.
PROZINC Insulin Is for Dogs and Cats
PROZINC insulin provides canine patients with extended duration of action, feline patients with rapid glycemic control, and reduces clinical signs of diabetes mellitus.1,2 With its proven safety profile, it’s the diabetes treatment you can feel confident sending your patients home with.
PROZINC Insulin in Canine Patients
Learn how the PROZINC difference can benefit your diabetic canine patients.
PROZINC Insulin in Feline Patients
Learn how the PROZINC difference can benefit your diabetic feline patients.
- Ward CR, Christiansen K, Li J, et al. Field efficacy and safety of protamine zinc recombinant human insulin in 276 dogs with diabetes mellitus. Domest Anim Endocrinol. 2021;75:106575.
- Nelson RW, Henley K, Cole C, et al. Field safety and efficacy of protamine zinc recombinant human insulin for treatment of diabetes melitus in cats. J Vet Intern Med. 2009;23:797-802.
- PROZINC® (protamine zinc recombinant human insulin) [Freedom of Information Summary; NADA 141-297]. St. Joseph, MO: Boehringer Ingelheim Vetmedica, Inc.; 2009.
PROZINC® is a registered trademark of Boehringer Ingelheim Animal Health USA Inc. BI-CONNECT™ and logo are trademarks of Boehringer Ingelheim Animal Health USA Inc. All other trademarks are the property of their respective owner. ©2022 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved. All other trademarks are the property of their respective owner.
PROZINC® (protamine zinc recombinant human insulin) is for use in dogs and cats only. Keep out of the reach of children. Owners should be advised to observe for signs of hypoglycemia (low blood sugar). Signs may include weakness, depression, behavioral changes, muscle twitching, and anxiety. In severe cases of hypoglycemia, seizures and coma can occur. Hypoglycemia can be fatal if an affected animal does not receive prompt treatment. PROZINC should not be used during episodes of hypoglycemia (low blood sugar). Appropriate veterinary monitoring of blood glucose, adjustment of insulin dose and regimen as needed, and stabilization of diet and activity help minimize the risk of hypoglycemic episodes. The attending veterinarian should evaluate other adverse reactions on a case-by-case basis to determine if an adjustment in therapy is appropriate, or if alternative therapy should be considered. The safety and effectiveness of PROZINC in puppies, kittens, or breeding, pregnant, and lactating animals has not been evaluated. For more information, please see full prescribing information.