swine production staff walking inside pig pen

Ileitis

Protect Your Herd Against Ileitis

Porcine proliferative enteropathy, or ileitis, caused by Lawsonia intracellularis, is a common bacterial illness, with greater than 95% prevalence,1 that reduces both growth rate and feed efficiency.2,3 Ileitis is an enteric — or intestinal — disease that forms lesions within the small intestine of the pig, particularly within the ileum. Ileitis can affect weight gain in pigs of all ages, with the biggest impact on late nursery through finishing.

Understanding Ileitis

Clinical Signs

The disease occurs in two clinical forms: PIA (porcine  ...

The disease occurs in two clinical forms: PIA (porcine intestinal adenomatosis), characterized by gray diarrhea, or PHE (proliferative hemorrhagic enteropathy), characterized by bloody diarrhea. Even when it occurs subclinically, the economic impact of ileitis can be significant. 

Subclinical Ileitis

Prevalence of ileitis is often underestimated, as  ...

Prevalence of ileitis is often underestimated, as subclinically infected pigs may not present clinical signs, and thus go undetected or undiagnosed. Monitoring for Lawsonia intracellularis spread can be a valuable tool in understanding the infection status in a herd.

Controlling Ileitis

While initial outbreaks of the disease can be  ...

While initial outbreaks of the disease can be treated with antibiotics, vaccination provides a more sustainable solution to protect pigs against the health and performance impacts of Ileitis.

Enterisol Ileitis Lawsonia Intracellularis Vaccine product

Discover Enterisol® Ileitis

ENTERISOL ILEITIS has a proven 20-year track record of supporting gut health and improving pig performance.4–9

Discover Enterisol® Ileitis

ENTERISOL ILEITIS has a proven 20-year track record of supporting gut health and improving pig performance.4–9

Enterisol Ileitis Lawsonia Intracellularis Vaccine product

Recent Ileitis Resources

a pig drinking water mixed with Enterisol Ileitis vaccine

Enterisol® Ileitis: What We Have Learned in 20 Years of Controlling Lawsonia intracellularis

A summary of 20 years of research and key learnings about Lawsonia intracellularis and how to control it.

Enterisol® Ileitis: What We Have Learned in 20 Years of Controlling Lawsonia intracellularis

A summary of 20 years of research and key learnings about Lawsonia intracellularis and how to control it.

a pig drinking water mixed with Enterisol Ileitis vaccine

How Lawsonia intracellularis Negatively Impacts Nutrient Absorption

Industry-leading swine veterinarians discuss the importance of understanding enterocytes and
how Lawsonia intracellularis negatively impacts
nutrient absorption. 

Clinical Forms of  Lawsonia  intracellularis and Differential Diagnoses

Industry-leading swine veterinarians discuss the clinical presentations of ileitis, the impacts of the disease at clinical and subclinical levels, and differential diagnoses to consider when investigating potential ileitis outbreaks. 

References

1 Vannucci F, Gebhart C, McOrist S. Proliferative enteropathy. In: Zimmerman J, Karriker L, Ramirez A, et al., eds. Diseases of swine. 11th ed. West Sussex: Wiley-Blackwell, 2019;898–911. 
2 Paradis M, Gebhart C, Toole D, et al. Subclinical ileitis: Diagnostic and performance parameters in a multi-dose mucosal homogenate challenge model. J Swine Heath Prod 2012 ;20(3):137–141.  

3 Helm E, Outhouse A, Schwartz K, et al. Impact of Mycoplasma hyopneumoniae and Lawsonia intracellularis on the performance of pigs divergently selected for feed efficiency. J Anim Sci 2018;96 (2):462–472. 

4 Kolb J, Sick F. Summary of field trials implementing Enterisol® Ileitis against ileitis, in Proceedings. 33rd Annu Meet AASV 2003;243–244. 

5 Ochoa, et al. 2020. 

6 Peiponen, et al. 2018. 

7 Park, et al. 2013. 

8 Nerem J. Lawsonia intracellularis vaccination as an alternative to dietary antimicrobial medication in finishing swine. Safe Pork 2009;185–187. 

9 Leite F, Cline G, Waddell J, et al. Enterisol® Ileitis: What we have learned in 20 years of controlling Lawsonia intracellularis. Available at: https://www.swineresource.com/enteric-diseases/ileitis/enterisol-ileitis-what-we-have-learned-in-twenty-years-controlling-lawsonia-intracellularis. Accessed May 18, 2022. 

ENTERISOL® is a registered trademark of Boehringer Ingelheim Vetmedica GmbH, used under license. ©2022 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All Rights Reserved. US-POR-0143-2022