Glaesserella parasuis (GPS), the etiological agent of Glasser’s Disease, is considered one of the main infection problems in the nursery, as it occurs subsequent to stressful events like weaning. While GPS strains are classified into 15 serovars, serovar type 5 is the most common strain in circulation.1
Clinical signs are mainly observed in four- to eight-week-old-pigs. Clinical signs of acute GPS infection include high fever, coughing, abdominal breathing, swollen joints with lameness and central nervous signs like trembling.
GPS is the fifth most frequently detected pathogen on respiratory tissues since 2017, and is frequently associated with co-infections of respiratory diseases like porcine reproductive and respiratory syndrome (PRRS), influenza A virus in swine (IAV-S), Mycoplasma hyorhinis (M. hyorhinis), and Streptococcus suis (S. suis).2
GPS can cause sudden death in piglets. Antibiotics are widely used to prevent and control GPS disease, but aligned with judicious antibiotic use, vaccination strategies are recommended to prevent systemic infection and mortality.
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